After menopause, however, the levels of estrogen in a woman’s body drop significantly and can contribute to the higher risks of cardiovascular disease,” explains Vera Rigolin,MD, associate director of the Center for Women’s Cardiovascular Health in the Bluhm Cardiovascular Institute of Northwestern Memorial Hospital.

Weight gain is also a factor that may play a role in postmenopausal risk of heart disease. Maintaining a healthy weight often becomes difficult after your body experiences a change in hormone levels. Extra mass can take a toll on the body causing physical inactivity, high blood pressure, diabetes, and high cholesterol, all risk factors that can lead to heart attack and stroke.